inocoterone acetate in a sentence
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- Inocoterone acetate was investigated for the treatment of acne but showed only modest ( albeit statistically significant ) efficacy in clinical trials.
- Inocoterone acetate is actually not a silent antagonist of the androgen receptor but rather a weak partial agonist, similarly to steroidal antiandrogens like cyproterone acetate.
- An acetate ester, inocoterone acetate, shows greater antiandrogen activity and was developed as a topical medication for the treatment of acne but showed only modest effectiveness in clinical trials and similarly was never marketed.
- These include the steroidal AR antagonists cortexolone 17?-propionate, cyproterone, rosterolone, and topterone and the non-steroidal AR antagonists cioteronel, inocoterone acetate, RU-22930, RU-58642, and RU-58841.
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